STORAGE & STABILITY
- The kit should be stored at 2-30°C until the expiry date printed on the sealed pounch.
- The test must remain in the sealed pouch until use.
- Do not freeze.
- Care should be taken to protect the components of the kit from contamination of dispensing equipment, containers or reagents can lead to false results.
INTENDED USE
The AMP One Step Amphetamine Test Device (Urine) is a lateral now chromatographic immunoassay for the detection of Amphetamine in human urine. This assay provides only a preliminary analytical test result. A more specific alternate chemical method must be used in order to obtain a confirmed analytical result. Gas chromatography/mass spectrometry (GC/MS) is the preferred confirmatory method. Clinical consideration and professional judgment should be applied to any drug of abuse test result, particularly when preliminary positive results are used.
INTRODUCTION
Amphetamine is a Schedule II controlled substance available by presecription (Dexedrine®) and is also available on the illicit market. Amphetamines are a class of potent sympathomimetic agents with therapeutic applications. They are chemically related to the human body's natural catecholamines: epinephrine and norepinephrine. Acute higher doses lead to enhanced stimulation of the central nervous system and induce euphoria, alertness, reduced appetite. and a sense uf increased energy and power. Cardiovascular responses to Amphetamines include increased blood pressure and cardiac arrhythmias. More acute responses produce anxiety, paranoia, hallucinations, and psychotic behavior. The effects of Amphetamines generally last 2-4 hours following use, and the drug has a half-life ot 4-24 hours in the body. About 30% of Amphetamines arc excreted in the urine in unchanged form, with the remainder as hydroxylated and deaminated derivatives. The AMP One Step Amphetamine Test Devire (Urine) is a rapid urine screening test that can be performed without the use of an instrument. The test utilizes a monoclonal antibody to selectively detect elevated levels of Amphetamines in urine. The AMP One Step Amphetamine Test Device (Urine) yields a positive result when Amphetamines in urine exceed 1,000 ng/mL.
